Bosch Amate, XavierSerra García, LauraAlamon Reig, FrancescMartí Martí, IgnasiGil Lianes, JavierGiavedoni, PriscilaMascaró Galy, José Manuel2024-11-212024-11-212022-08-010004-8380https://hdl.handle.net/2445/216669Granuloma annulare (GA) is a granulomatous, idiopathic, inflammatory skin disorder characterized by the formation of papules and plaques with annular and acral distribution. GA is often limited and self-resolving, but in some cases, it can be generalized and refractory to treatments. New advances in the pathophysiology of GA have favoured Janus kinase (JAK) inhibitors as a promising therapeutic option.1,2 Here, we report three cases of resistant generalized GA successfully treated with tofacitinib.4 p.application/pdfengcc-by (c) Bosch Amate, Xavier et al., 2022http://creativecommons.org/licenses/by/4.0Malalties de la pellInhibidors enzimàticsResposta immunitàriaMedicamentsSkin diseasesEnzyme inhibitorsImmune responseDrugsinfo:eu-repo/semantics/article7515742024-11-21info:eu-repo/semantics/openAccess35605155