Solé Arjó, DanielMariani, FrancescoBennasar Fèlix, M. LluïsaFernández Cadenas, Israel2019-01-302019-01-302016-04-151433-7851https://hdl.handle.net/2445/127737A palladium‐catalyzed carbene insertion into C(sp3)−H bonds leading to pyrrolidines was developed. The coupling reaction can be catalyzed by both Pd0 and PdII, is regioselective, and shows a broad functional group tolerance. This reaction is the first example of palladium‐catalyzed C(sp3)−C(sp3) bond assembly starting from diazocarbonyl compounds. DFT calculations revealed that this direct C(sp3)−H bond functionalization reaction involves an unprecedented concerted metalation-deprotonation step.4 p.application/pdfeng(c) Wiley-VCH, 2016Pal·ladi (Element químic)CatàlisiSíntesi orgànicaComplexitat computacionalQuímica organometàl·licaPalladiumCatalysisOrganic synthesisComputational complexityOrganometallic chemistryinfo:eu-repo/semantics/article6591352019-01-30info:eu-repo/semantics/openAccess27079473