Urraza-Robledo, Arguiñe IvonneGiralt i Oms, MartaGonzález-Galarza, Faviel FranciscoVillarroya i Gombau, FrancescMiranda Pérez, Alberto AlejandroRuiz Flores, PabloGutiérrez Pérez, María ElenaDomingo, Pere (Domingo Pedrol)López-Márquez Francisco Carlos2022-03-212022-03-212021-05-211932-6203https://hdl.handle.net/2445/184269Antiretroviral therapy has significantly improved prognosis in treatment against HIV infection, however, prolonged exposure is associated to cardiovascular diseases, lipodystrophy, type 2 diabetes, insulin resistance, metabolic alteration, as obesity which includes the accumulation of oxidative stress in adipose tissue. FGF21 is a peptide hormone that is known to regulate glucose and lipid metabolism. FGF21 is expressed and secreted primarily in the liver and adipose tissue, promoting oxidation of glucose/fatty acids and insulin sensitivity. Alterations in FGF21 may be associated with the development of insulin resistance, metabolic syndrome and cardiovascular disease. We hypothesized that FGF21 protein levels are associated with metabolic abnormalities, placing special attention to the alterations in relation to the concurrence of overweight/obesity in people living with HIV (PLWH).12 p.application/pdfengcc-by (c) Urraza-Robledo, Arguiñe Ivonne et al., 2021https://creativecommons.org/licenses/by/4.0/Infeccions per VIHHormones peptídiquesHIV infectionsPeptide hormonesinfo:eu-repo/semantics/article7158542022-03-21info:eu-repo/semantics/openAccess