Ibañes Miguez, MartaMut Sbert, Macià2020-10-212020-10-212020-06https://hdl.handle.net/2445/171392Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutora: Marta Ibañes MiguezDuring tissue development, cells differentiate creating a cellular pattern thanks to communication frameworks like the one studied, the Notch signalling pathway. In such mechanisms a cell interacts with the surrounding cells through proteins called ligands. With a numerical simulation program we manage to confirm the formation of cell patterns and doing a lineal stability analysis we find under which conditions the pattern can arise for a sustained signal activation. Furthermore, when implementing a transitory pulsating signal dynamics we find that a minimum interaction time is required if the cells are to differentiate5 p.application/pdfengcc-by-nc-nd (c) Mut, 2020http://creativecommons.org/licenses/by-nc-nd/3.0/es/Lligands (Bioquímica)Formació de patrons (Física)Treballs de fi de grauLigands (Biochemistry)Pattern formation (Physical sciencesBachelor's thesesComputational analysis of signal dynamics induced by ligandsinfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/openAccess