Angelini, Thomas E.Hannezo, EdouardTrepat Guixer, XavierFredberg, Jeffrey J.Weitz, David A.2019-05-302019-05-302010-04-230031-9007https://hdl.handle.net/2445/134162Most eukaryotic cells sense and respond to the mechanical properties of their surroundings. This can strongly influence their collective behavior in embryonic development, tissue function, and wound healing. We use a deformable substrate to measure collective behavior in cell motion due to substrate mediated cell-cell interactions. We quantify spatial and temporal correlations in migration velocity and substrate deformation, and show that cooperative cell-driven patterns of substrate deformation mediate long-distance mechanical coupling between cells and control collective cell migration.4 p.application/pdfeng(c) American Physical Society, 2010Cèl·lules eucariotesMigració cel·lularEukaryotic cellsCell migrationinfo:eu-repo/semantics/article6131652019-05-30info:eu-repo/semantics/openAccess20482085