Van Looy, BartGrabowska, MarcelinaVlaisavljevic, VesnaLecocq, CatherineDebackere, Koenraad2024-06-212024-07-162024-01-171087-0156https://hdl.handle.net/2445/213515Over a timespan of a few decades, biotechnology evolved from an area of fundamental scientific enquiry into a variety of different application areas (ranging from pharmaceuticals/health care to agriculture, food and materials) with an ever increasing economical footprint. By using patent and publication-based indicators, we aim to address several relevant aspects of the technological performance of regions in the field of biotechnology. We examine the role of anchor tenants: is the presence of those still essential to flourish as a biotech region? Furthermore, we zoom in on the different mechanisms through which science (its multifaceted role) contributes to local technology development. Our study provides in-depth longitudinal analysis that adopts the long-term perspective of biotech globally in order to describe the enablers of regional growth. Our research confirms: the importance of first mover advantage as being a top region in the early phase of the industry sustains the progress; science quantity and quality matters; entrepreneurial orientation of universities does make a difference. Adopting the long view pays off as regions benefit from the presence of multiple firms, rather than relying on the anchor tenant as an engine for growth. The S&T collaborations beyond the boundaries of region account for potential contributions.6 p.application/pdfeng(c) Nature Publishing Group, 2024BiotecnologiaSistemes productius localsEmprenedoriaBiotechnologyIndustrial clustersEntrepreneurshipinfo:eu-repo/semantics/article7450942024-06-21info:eu-repo/semantics/openAccess