Barnadas Solé, CristinaZerón-Rugerio, María FernandaFoncillas Corvinos, JavierDíez Noguera, AntoniCambras Riu, TrinitatIzquierdo Pulido, Maria2026-01-222026-01-222021-12-010742-0528https://hdl.handle.net/2445/225947Advances in research have linked alterations of circadian rhythms with obesity. However, few</p><p>studies have focused on the recovery of the circadian expression after a weight loss treatment.</p><p>Our aim was to study the alterations of the circadian rhythmicity due to morbid obesity and the</p><p>recovery of the circadian pattern after weight loss in a cohort of patients who underwent sleeve</p><p>gastrectomy. For this purpose, 41 patients with severe obesity (75% women; age [mean (SD)]</p><p>49.7 ± 10 years; BMI 44.3 ± 6.2 kg/m2) were monitored before bariatric surgery and 9 months</p><p>afterward. On both occasions, activity and wrist temperature were determined by actigraphy and</p><p>were related with weight loss. Anthropometric, biochemical, and sleep-related variables, along with</p><p>dietary intake and physical activity, were analyzed in relation with circadian rhythmicity. Results</p><p>show significant differences in the circadian expression before and after 9 months of bariatric</p><p>surgery, with more stable and less fragmented rhythms after weight loss. Moreover, only after</p><p>surgery were the circadian variables associated to sleep timing and chronotype. The findings of this</p><p>study indicate that weight loss treatment in patients with morbid obesity improves the circadian</p><p>rhythm expression, and in such a way that it could be associated with better sleep quality.</p><p>Moreover, it allows the recovery of the relationship between sleep patterns and circadian rhythm</p><p>that was lost due to the obesity.12 p.application/pdfeng(c) Informa Healthcare, 2021ObesitatRitmes circadiarisCirurgiaObesityCircadian rhythmsSurgeryinfo:eu-repo/semantics/article7149532026-01-22info:eu-repo/semantics/openAccess