Cyclocondensation reactions of 2-acyl-3-indoleacetic acid derivatives with phenylglycinol. Enantioselective synthesis of 1-substituted tetrahydro-b-carboline alkaloids

Amat Tusón, MercedesSubrizi, FabianaElias, VivianeLlor Brunés, NúriaMolins, EliesBosch Cartes, Joan2020-06-042020-06-042012-031434-193Xhttps://hdl.handle.net/2445/164192Cyclocondensation reactions between a variety of 2‐acyl‐3‐indoleacetic acid derivatives and (R )‐phenylglycinol were studied. Successful results were obtained from N ‐alkyl keto acid derivatives. The resulting tetracyclic lactams provide straightforward access to enantiopure 1‐substituted tetrahydro‐β‐carboline alkaloids.8 p.application/pdfeng(c) Wiley-VCH, 2012Síntesi asimètricaAlcaloidesLactamesAsymmetric synthesisAlkaloidsLactamsCyclocondensation reactions of 2-acyl-3-indoleacetic acid derivatives with phenylglycinol. Enantioselective synthesis of 1-substituted tetrahydro-b-carboline alkaloidsinfo:eu-repo/semantics/article6033012020-06-04info:eu-repo/semantics/openAccess