Enantioselective formal synthesis of (+)-madangamine A

Are, CelestePérez Bosch, MariaBosch Cartes, JoanAmat Tusón, Mercedes2019-07-122020-05-272019-05-271359-7345https://hdl.handle.net/2445/137117An enantioselective formal synthesis of the marine alkaloid madangamine A using phenylglycinol-derived lactam 1 as the starting enantiomeric scaffold is reported. The synthesis involves the construction of the C-9 substituted diazatricyclic ABC core and the final closure of D and E rings from the polyunsaturated skipped intermediate 19.application/pdfeng(c) Are, Celeste et al., 2019AlcaloidesLactamesCompostos heterocíclicsSíntesi orgànicaAlkaloidsLactamsHeterocyclic compoundsOrganic synthesisEnantioselective formal synthesis of (+)-madangamine Ainfo:eu-repo/semantics/article6903292019-07-12info:eu-repo/semantics/openAccess31165795