Arévalos, VictorOrtega Paz, LuisFernandez Rodríguez, DiegoJiménez Díaz, Víctor AlfonsoBañeras Rius, JordiCampo, GianlucaRodríguez Santamarta, MiguelPérez de Prado, ArmandoGómez Menchero, AntonioDíaz Fernández, José FranciscoScardino, ClaudiaGonzalo, NievesPernigotti, AlbertoAlfonso, FernandoJesús Amat-santos, IgnacioSilvestro, AntonioIelasi, AlfonsoTorre, José María de laBastidas, GabrielaGómez Lara, JosepSabaté, ManelBrugaletta, SalvatoreCV Covid-19 Registry Investigators2021-09-132021-09-132021-07-29https://hdl.handle.net/2445/179981Background: Patients presenting with the coronavirus-2019 disease (COVID-19) may have a high risk of cardiovascular adverse events, including death from cardiovascular causes. The long-term cardiovascular outcomes of these patients are entirely unknown. We aim to perform a registry of patients who have undergone a diagnostic nasopharyngeal swab for SARS-CoV-2 and to determine their long-term cardiovascular outcomes. Study and design: This is a multicenter, observational, retrospective registry to be conducted at 17 centers in Spain and Italy (ClinicalTrials.gov number: NCT04359927). Consecutive patients older than 18 years, who underwent a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV2 in the participating institutions, will be included since March 2020, to August 2020. Patients will be classified into two groups, according to the results of the RT-PCR: COVID-19 positive or negative. The primary outcome will be cardiovascular mortality at 1 year. The secondary outcomes will be acute myocardial infarction, stroke, heart failure hospitalization, pulmonary embolism, and serious cardiac arrhythmias, at 1 year. Outcomes will be compared between the two groups. Events will be adjudicated by an independent clinical event committee. Conclusion: The results of this registry will contribute to a better understanding of the long-term cardiovascular implications of the COVID19.application/pdfengcc by (c) Arévalos, Victor et al., 2021http://creativecommons.org/licenses/by/3.0/es/COVID-19Sistema cardiovascularCOVID-19Cardiovascular systeminfo:eu-repo/semantics/article2021-09-10info:eu-repo/semantics/openAccess34324524