Mont Girbau, LluísRoca Luque, IvoAlthoff, Till F.2024-01-242024-01-242021-12-112050-3377https://hdl.handle.net/2445/206230Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique opportunity to assess ablation lesions non-invasively. In the atrium, LGE-MRI has been shown to accurately detect and localise gaps in ablation lines. With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. Even LGE-MRI-guided repeat pulmonary vein isolation has been demonstrated to be feasible as a standalone approach. LGE-MRI-based lesion assessment may also be of value to evaluate the efficacy of ventricular ablation. In this respect, the elimination of LGE-MRI-detected arrhythmogenic substrate may serve as a potential endpoint, but validation in clinical studies is lacking. Despite holding great promise, the widespread use of LGE-MRI is still limited by the absence of standardised protocols for image acquisition and post-processing. In particular, reproducibility across different centres is impeded by inconsistent thresholds and internal references to define fibrosis. Thus, uniform methodological and analytical standards are warranted to foster a broader implementation in clinical practice.11 p.application/pdfengcc by (c) Mont Girbau, Lluís et al., 2021http://creativecommons.org/licenses/by/3.0/es/Malalties cardiovascularsRessonància magnèticaCardiovascular diseasesMagnetic resonanceinfo:eu-repo/semantics/article2023-07-06info:eu-repo/semantics/openAccess930805235444808