Hermo Outeiral, Ma. del PilarNemutlu, E.Barbosa Torralbo, JoséBarrón Bueno, Dolores2020-05-052020-05-052011-04-050269-3879https://hdl.handle.net/2445/158646This paper presents the multiresidue determination of the series of quinolones regulated by the European Union (marbofloxacin, ciprofloxacin, danofloxacin, enrofloxacin, sarafloxacin, difloxacin, oxolinic acid and flumequine) in bovine and porcine plasma using capillary electrophoresis and liquid chromatography with ultraviolet detection (CE-UV, LC-UV), liquid chromatography-mass spectrometry and -tandem mass spectrometry (LC-MS, LC-MS/MS) methods. These procedures involve a sample preparation by solid-phase extraction for clean-up and preconcentration of the analytes before their injection into the separation system. All methods give satisfactory results in terms of linearity, precision, accuracy and limits of quantification. The suitability of the methods to determine quinolones was evaluated by determining the concentration of enrofloxacin and ciprofloxacin in real samples from pig plasma and cow plasma15 p.application/pdfeng(c) Wiley, 2011AntibiòticsElectroforesi capil·larQuinolonesCromatografia de líquidsAntibioticsCapillary electrophoresisQuinolone antibacterial agentsLiquid chromatographyinfo:eu-repo/semantics/article5783932020-05-05info:eu-repo/semantics/openAccess