Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivatives

Bosch Hereu, LluísMouscadet, Jean-FrancoisNi, Xio-JuVilarrasa i Llorens, Jaume2020-05-182020-05-182011-02-160040-4039https://hdl.handle.net/2445/160861N-Hydroxy-4-oxoquinazoline-2-carboxamide derivatives (cyclic hydroxamic acids) and related pyrido- and thieno-substituted analogues, as well as a N-hydroxyhypoxanthine-2-carboxamide were synthesised for the first time, by means of a four-step sequence that involves a smooth reaction of aminohydroxamates with methyl trimethoxyacetate. Other strategies were unsuccessful.4 p.application/pdfeng(c) Elsevier Ltd, 2011Síntesi orgànicaMecanismes de reacció (Química)Organic synthesisReaction mechanisms (Chemistry)Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivativesinfo:eu-repo/semantics/article5966322020-05-18info:eu-repo/semantics/openAccess