Heras, MartaAlonso Espias, MariaArencibia, OctavioMinig, LucasMartí, LolaDiestro, Maria DoloresCespedes, JuanNíguez, IsabelGil Ibáñez, BlancaDíaz Feijoo, BertaLlueca, AntoniRosado, ClaudiaIacoponi, SaraLopez de la Manzanara, CarlosMorales, SaraFernández Galguera, María JoséCano, AnaGorostidi, MikelZapardiel, Ignacio2024-08-292024-08-292024-07-032075-4418https://hdl.handle.net/2445/214871Background: to prove the effectivity of fertility-sparing procedures in early-stage ovarian cancer by assessing pregnancy rates and obstetrical outcomes. Methods: we performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients from 18 to 40 years old with diagnosis of early-stage ovarian cancer, epithelial (EOC) or non-epithelial (non-EOC), from January 2010 to December 2019. Data on the use of assisted reproductive techniques, pregnancy attempts and obstetrical outcomes were collected. Results: a total of 150 patients met inclusion criteria, 70 (46.6%) EOC and 80 (53.4%) non-EOC. Pregnancy attempts were reported in 51 (34%) patients, with 42 (28%) patients carrying the pregnancy to term. Among them, 30 (71.4%) underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. A total of 32 (76.1% patients) had spontaneous pregnancies and 10 (23.9%) required in vitro fertilization. There was only one (2.4%) complication reported. Vaginal delivery was reported in twenty-nine (69%) patients and cesarean section in five (11.9%) patients. Conclusions: fertility-sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complications. The selection of patients must consider strict criteria in order to maintain a good prognosis.10 p.application/pdfengcc by (c) Heras, Marta et al, 2024http://creativecommons.org/licenses/by/3.0/es/Càncer d'ovariFecunditatOvarian cancerFertilityinfo:eu-repo/semantics/article2024-07-31info:eu-repo/semantics/openAccess39001314