Piquer García, IreneCereijo Téllez, RubénCorral-Pérez, JuanPellitero, SilviaMartínez, EvaTaxerås, Siri D.Tarascó, JordiMoreno, PauBalibrea, JoséPuig Domingo, ManuelSerra i Cucurull, DolorsHerrero Rodríguez, LauraJiménez-Pavón, DavidLerin, CarlesVillarroya i Gombau, FrancescSánchez-Infantes, David2020-06-112020-06-300960-8923https://hdl.handle.net/2445/165144Background: In contrast to the energy-storing role of white adipose tissue (WAT), brown adipose tissue (BAT) acts as the main site of non-shivering thermogenesis in mammals and has been reported to play a role in protection against obesity and associated metabolic alterations in rodents. Infrared thermography (IRT) has been proposed as a novel non-invasive, safe, and quick method to estimate BAT thermogenic activation in humans. The aim of this study is to determine whether the IRT could be a potential new tool to estimate BAT thermogenic activation in patients with severe obesity in response to bariatric surgery. Methods: Supraclavicular BAT thermogenic activation was evaluated using IRT in a cohort of 31 patients (50 ± 10 years old, BMI = 44.5 ± 7.8; 15 undergoing laparoscopy sleeve gastrectomy and 16 Roux-en-Y gastric bypass) at baseline and 6 months after a bariatric surgery. Clinical parameters were determined at these same time points. Results: Supraclavicular BAT-related activity was detected in our patients by IRT after a cooling stimulus. The BAT thermogenic activation was higher at 6 months after laparoscopy sleeve gastrectomy (0.06 ± 0.1 vs 0.32 ± 0.1), while patients undergoing to a roux-en-Y gastric bypass did not change their thermogenic response using the same cooling stimulus (0.09 ± 0.1 vs 0.08 ± 0.1). Conclusions: Our study postulates the IRT as a potential tool to evaluate BAT thermogenic activation in patients with obesity before and after a bariatric surgery. Further studies are needed to evaluate differences between LSG technique and RYGB on BAT activation. Keywords: Brown adipose tissue; Infrared thermography; Metabolic surgery; Obesity.7 p.application/pdfeng(c) Springer Verlag, 2020ObesitatTermografia mèdicaCirurgia de l'obesitatObesityMedical thermographyObesity surgeryinfo:eu-repo/semantics/article6995902020-06-11info:eu-repo/semantics/openAccess