Narváez García, Francisco JavierDíaz-Torné, CésarJuanola, XavierGeli, C.Llobet, Josep MariaNolla Solé, Joan MiquelDíaz-López, C.2012-03-052012-03-0520090003-4967https://hdl.handle.net/2445/22470Systemic-onset juvenile idiopathic arthritis (SOJIA), formerly called Still’s disease, is a subset of juvenile arthritis that describes patients with fever, rash, arthritis, serositis and visceromegaly. In up to 30% of cases the disease has a chronic course and management requires high doses of glucocorticoids, disease-modifying antirheumatic drugs (DMARD), tumour necrosis factor alpha (TNFα) inhibitors or anakinra.1–6 However, this therapeutic arsenal is unable to control the disease in all patients.#N##N#Recently, rituximab, a chimeric anti-CD20 monoclonal antibody, has been successfully used in two patients with refractory adult-onset Still’s disease.7 As the similarity of clinical and laboratory features present in SOJIA and adult-onset Still’s disease implies that these conditions have similar …2 p.application/pdfeng(c) BMJ Publishing Group Ltd, 2009ArtritisJovesTerapèuticaArthritisYouthTherapeuticsinfo:eu-repo/semantics/article580828info:eu-repo/semantics/openAccess