Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops

Benabou Zdaou, SanaeFerreira Aguilera, RubénAviñó Andrés, AnnaGonzález, CarlosLyonnais, SébastienSolà Vilarrubias, MariaEritja i Casadellà, RamonJaumot Soler, JoaquimGargallo Gómez, Raimundo2013-09-192013-09-192013-09-060304-4165https://hdl.handle.net/2445/46204Cytosine-and guanine-rich regions of DNA are capable of forming complex structures named i-motifs and G-quadruplexes, respectively. In the present study the solution equilibria at nearly physiological conditions of a 34 -bases long cytosine-rich sequence and its complementary guanin e-rich strand corresponding to the first intron of the n-mycgene were studied. Both sequences , not yet studied, contain a 12 - base tract capable of forming stable hairpins inside the i-motif and G-quadruplex structures, respectively ...50 p.application/pdfeng(c) Elsevier B.V., 2013ADNRNAÀcids nucleicsAnàlisi multivariableCromatografiaDNARNANucleic acidsMultivariate analysisChromatographySolution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loopsinfo:eu-repo/semantics/article6281712013-09-19info:eu-repo/semantics/openAccess24012973