Gamba, IlariaSalvadó, IriaBrissos, Rosa F.Gámez Enamorado, PatrickBrea, JoséLoza, María IsabelVázquez, M. EugenioVázquez López, Miguel2017-07-212017-07-212016-01-211359-7345https://hdl.handle.net/2445/114162We demonstrate the application of solid-phase peptide synthesis methods for the straightforward assembly of polynuclear Ir(III) organometallopeptides, and show that their oligoarginine derivatives exhibit high DNA binding affinity, sequence selectivity, and high cytotoxicity towards a set of cancer cell lines.4 p.application/pdfeng(c) Gamba, Ilaria et al., 2016Síntesi de pèptidsFísica de l'estat sòlidADNCàncerPeptide synthesisSolid state physicsDNACancerHigh-affinity sequence-selective DNA binding by iridium(III) polypyridyl organometallopeptidesinfo:eu-repo/semantics/article6561222017-07-21info:eu-repo/semantics/openAccess26611126