Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

Pérez de Vega, M.J.García-López, M.T.Zaccaro, LauraRoyo Expósito, MiriamAlbericio Palomera, FernandoFernández-Carvajal, A.Ferrer-Montiel, A.González-Muñiz, R.2014-03-122014-03-122010-07-151420-3049https://hdl.handle.net/2445/51423Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N-terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.10 p.application/pdfengcc-by (c) Pérez de Vega, M.J. et al., 2010http://creativecommons.org/licenses/by/3.0/esSíntesi en fase sólidaCanals iònicsBioquímicaAnalgèsicsCiències de la salutProteïnesDianes farmacològiquesSolid-phase synthesisIon channelsBiochemistryAnalgesicsMedical sciencesProteinsDrug targetingSolid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockersinfo:eu-repo/semantics/article6138992014-03-12info:eu-repo/semantics/openAccess20657400