Bennasar Fèlix, M. LluïsaZulaica Gallego, EsterSolé Arjó, DanielRoca Estrem, TomàsGarcía Díaz, DaviniaAlonso Serrano, Sandra2020-05-282020-05-282009-10-140022-3263https://hdl.handle.net/2445/162821An indole-templated ring-closing metathesis or a 2-indolylacyl radical cyclization constitute the central steps of two alternative approaches developed to assemble the tricyclic ABC substructure of the indole alkaloid apparicine. From this key intermediate, an intramolecular vinyl halide Heck reaction accomplished the closure of the strained 1-azabicyclo[4.2.2]decane framework of the alkaloid with concomitant incorporation of the exocyclic alkylidene substituents.10 p.application/pdfeng(c) American Chemical Society , 2009Síntesi orgànicaAlcaloidesMetàtesi (Química)Organic synthesisAlkaloidsMetathesis (Chemistry)info:eu-repo/semantics/article5716032020-05-28info:eu-repo/semantics/openAccess19824689