Daitch, VeredYelin, DanaAwwad, MuhammadGuaraldi, GiovanniMilić, JovanaMussini, CristinaFalcone, MarcoTiseo, GiusyCarrozzi, LauraPistelli, FrancescoNehme, MayssamGuessous, IdrisKaiser, LaurentVetter, PaulineBordas Martínez, JaumeDurà Miralles, XavierPeleato Catalan, DoloresGudiol González, CarlotaShapira Lichter, IritAbecasis, DonnaLeibovici, LeonardYahav, DafnaMargalit, IliESCMID study group for infections in the elderly (ESGIE)2023-05-242023-05-242022-121201-9712https://hdl.handle.net/2445/198403Objectives: To describe long-COVID symptoms among older adults and to assess the risk factors for two common long-COVID symptoms: fatigue and dyspnea. Methods: This is a multicenter, prospective cohort study conducted in Israel, Switzerland, Spain, and Italy. Individuals were included at least 30 days after their COVID-19 diagnosis. We compared long-COVID symptoms between elderly (aged >65 years) and younger individuals (aged 18-65 years) and conducted univariate and multivariable analyses for the predictors of long-COVID fatigue and dyspnea. Results: A total of 2333 individuals were evaluated at an average of 5 months (146 days [95% confidence interval 142-150]) after COVID-19 onset. The mean age was 51 years, and 20.5% were aged >65 years. Older adults were more likely to be symptomatic, with the most common symptoms being fatigue (38%) and dyspnea (30%); they were more likely to complain of cough and arthralgia and have abnormal chest imaging and pulmonary function tests. Independent risk factors for long-COVID fatigue and dyspnea included female gender, obesity, and closer proximity to COVID-19 diagnosis; older age was not an independent predictor. Conclusion: Older individuals with long-COVID have different persisting symptoms, with more pronounced pulmonary impairment. Women and individuals with obesity are at risk. Further research is warranted to investigate the natural history of long-COVID among the elderly population and to assess possible interventions aimed at promoting rehabilitation and well-being.7 p.application/pdfengcc-by-nc-nd (c) Daitch, Vered et al., 2022https://creativecommons.org/licenses/by-nc-nd/4.0/COVID-19SARS-CoV-2Persones gransCOVID-19SARS-CoV-2Older peopleinfo:eu-repo/semantics/article7304872023-05-24info:eu-repo/semantics/openAccess36191820