Ramon Torrell, Josep M. (Josep Maria)Bruguera, Eugeni2018-11-302018-11-302009-04-21https://hdl.handle.net/2445/126638A prospective pragmatic interventional study was conducted to evaluate the effectiveness of varenicline for smoking cessation among a cohort of motivated smokers attending two smoking cessation clinics. Smokers between 18 and 65 years who had smoked 10 or more cigarettes per day were included. All participants received cognitive-behavioural varenicline according to approved dose and prescriptions. Continuous abstinence, validated by exhaled CO levels, was assessed in each control. A total of 264 smokers - 155 males (58.7%) and 109 females (41.3%) - were included. Mean age was 43.7, amount smoked was 23 cigarettes per day and 61.4% had at least one prior attempt to quit. The continuous abstinence rate at end of treatment (12 wks) was 58.3%. Conclusions: varenicline and cognitive-behavioural intervention are effective for smoking cessation with high continuous abstinence rates when are used in a clinical setting.9 p.application/pdfengcc by (c) Ramon Torrell, Josep M. (Josep Maria); Bruguera, Eugeni, 2009http://creativecommons.org/licenses/by/3.0/es/Tractament del tabaquismeSíndrome d'abstinènciaSmoking cessationDrug withdrawal symptomsinfo:eu-repo/semantics/article2018-07-25info:eu-repo/semantics/openAccess19440532