Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

Palicio, M.Blanco Guillermo, IgnacioTórtola, S.González, I.Marcuello, EugenioBrunet, JoanGonzalez Aguilera, Juan JosePeinado Morales, Miguel Á. (Miguel Ángel)Capellá, G. (Gabriel)Lluis, Fèlix2020-01-102020-01-102000-01-180007-0920https://hdl.handle.net/2445/147526A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function.3 p.application/pdfeng(c) Palicio, M. et al., 2000Càncer colorectalGenètica humanaEspanyaColorectal cancerHuman geneticsSpainIntron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancerinfo:eu-repo/semantics/article5172032020-01-10info:eu-repo/semantics/openAccess10682661