Colet, Josep ComínMainar, Antoni SicrasSalazar-Mendiguchía, JoelDel Campo Alonso, María IsabelEcheto, AinaraLarena, David VilanovaSánchez, Olga Delgado2024-01-042024-01-042023-07-252042-6313https://hdl.handle.net/2445/205244Aim: Healthcare resources usage and costs associated to nonvalvular atrial fibrillation (NVAF) were analyzed in Spain. Methods: This is an observational and retrospective study on patients with NVAF who started their treatment with apixaban or acenocoumarol between 1 January 2015 and 31 December 2017. Results: 2160 patients treated with apixaban were paired (1:1) with patients treated with acenocoumarol (propensity score matching). Apixaban reduced the incidence of strokes and systemic embolisms, minor and major bleedings and deaths, versus acenocoumarol. Apixaban led to reductions of 80, 55 and 43% in costs related to nursing visits, hospitalizations, and emergency visits, respectively, leading to annual cost savings of euro274/patient, from the perspective of society. Conclusion: Our results suggested that apixaban is a cost-effective alternative for patients with NVAF.14 p.application/pdfengcc by-nc-nd (c) Colet, Josep Comín et al., 2023http://creativecommons.org/licenses/by-nc-nd/3.0/es/Medicaments cardiovascularsAnàlisi cost-beneficiCardiovascular agentsCost effectivenessinfo:eu-repo/semantics/article2023-09-12info:eu-repo/semantics/openAccess37489950