Barbas Cañero, RafaelFont Bardia, Ma. MercedesParadkar, A.Hunter, C. A.Prohens López, Rafael2020-05-282020-05-282018-10-301528-7483https://hdl.handle.net/2445/162874New multicomponent solid forms of sildenafil have been discovered by means of a combined virtual/experimental cocrystal screening. Coformer selection of candidates was conducted based on an in silico screening method from a database of more than 2000 organic compounds, and the intensive experimental screen produced 23 new solid forms. Since the 12 coformers chosen have a combination of phenol and carboxylic acid groups, a variety of cocrystals, salts, and hybrid salt-cocrystals were discovered and characterized.39 p.application/pdfeng(c) American Chemical Society , 2018Àcids orgànicsSalsEstructura cristal·lina (Sòlids)Organic acidsSaltsLayer structure (Solids)info:eu-repo/semantics/article6930542020-05-28info:eu-repo/semantics/openAccess