García-Basteiro, Alberto L.Moncunill Piñas, GemmaTortajada, MartaVidal, MartaGuinovart, CaterinaJiménez, AlfonsSantano, RebecaSanz, SergiMéndez, SusanaLlupià Garcia, AnnaAguilar, RuthAlonso, SelenaBarrios, DianaCarolis, CarloCisteró, PauChóliz, EugeniaCruz, AngelineFochs, SilviaJairoce, Chenjerai Tobias SixpenceHecht, JochenLamoglia-Puig, MontserratMartínez Yoldi, Miguel JuliánMitchell, Robert AndrewOrtega, NataliaPey, NuriaPuyol, LauraRibes, MartaRosell, NeusSotomayor, PatriciaTorres, SaraWilliams, SaraBarroso, SoniaVilella i Morató, AnnaMuñoz Gutiérrez, JoséTrilla García, AntoniVarela, PilarMayor Aparicio, Alfredo GabrielDobaño, Carlota, 1969-2021-04-092021-04-092020-07-082041-1723https://hdl.handle.net/2445/176139Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a large hospital in Spain. Of the 578 participants recruited from 28 March to 9 April 2020, 54 (9.3%, 95% CI: 7.1-12.0) were seropositive for IgM and/or IgG and/or IgA against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) was 11.2% (65/578, 95% CI: 8.8-14.1). Among those with evidence of past or current infection, 40.0% (26/65) had not been previously diagnosed with COVID-19. Here we report a relatively low seroprevalence of antibodies among HCW at the peak of the COVID-19 epidemic in Spain. A large proportion of HCW with past or present infection had not been previously diagnosed with COVID-19, which calls for active periodic rRT-PCR testing in hospital settings.9 p.application/pdfengcc-by (c) García-Basteiro, Alberto L. et al., 2020http://creativecommons.org/licenses/by/3.0/esSARS-CoV-2ImmunoglobulinesEpidemiologiaSARS-CoV-2ImmunoglobulinsEpidemiologyinfo:eu-repo/semantics/article7027982021-04-09info:eu-repo/semantics/openAccess32641730