Valero González, GuillemLeón, Carlos M.Moyano i Baldoire, Albert2018-02-192018-02-192015-06-122300-4630https://hdl.handle.net/2445/119967Solvent effects in the L-tryptophan-catalyzed Mannich reaction between hydroxyacetone and glyoxylate imines have been examined. The use of a DMSO/1-butanol (4:1 v/v) mixture as solvent at rt provided the expected Mannich adducts in good yields, high anti-diastereoselectivity (up to 10.3:1 anti/syn ratio) and excellent enantioselectivities (up to >99.9% ee for the anti isomer)10 p.application/pdfengcc by-nc-nd (c) Valero González, Guillem et al., 2015http://creativecommons.org/licenses/by-nc-nd/3.0/es/AminoàcidsCatàlisi asimètricaAmino acidsEnantioselective catalysisinfo:eu-repo/semantics/article6688502018-02-19info:eu-repo/semantics/openAccess