Ruiz Romeu, EsterSantamaria Babí, Luis F.2021-06-112021-06-112017-07https://hdl.handle.net/2445/178163Focusing on the study of human memory CLA+ T cells to understand psoriasis pathology constitutes an innovative approach to explore the pathological mechanism of this chronic cutaneous inflammatory disease. CLA+ T cells can be considered peripheral cell biomarkers in the study of T-cell mediated human skin diseases. During the last few years, new evidences have been found that link streptococcal infection with IL-17 response in psoriasis by studying the interaction between Streptococcus pyogenes with CLA+ T cells and autologous epidermal cells. S. pyogenes constitutes the best clinically characterized trigger of psoriasis and by exploring its effect on CLA+ T cells and epidermal cells in psoriasis may allow understanding psoriasis by using patient’s clinical samples ex vivo.12 p.application/pdfengcc by (c) Ruiz Romeu, Ester 1 et al., 2017http://creativecommons.org/licenses/by/3.0/es/PsoriasiLimfòcitsPsoriasisLymphocytesinfo:eu-repo/semantics/bookPart303967info:eu-repo/semantics/openAccess