Prohens López, RafaelBarbas Cañero, RafaelFont Bardia, Ma. Mercedes2021-03-232021-04-262020-04-261528-7483https://hdl.handle.net/2445/175633The crystal structures of the three efinaconazole anhydrous forms have been solved by single-crystal X-ray diffraction showing a very rare case of nearly isostructural polymorphism. The analysis of their crystal structures revealed that forms I and III are 'quasi-isostructural' polymorphs and are morphotropically related to form II. The identical conformational and supramolecular environment can explain the concomitant polymorphism phenomenon observed for this important active pharmaceutical ingredient.10 p.application/pdfeng(c) American Chemical Society , 2020Processos químicsEstructura cristal·lina (Sòlids)Chemical processesLayer structure (Solids)info:eu-repo/semantics/article7096302021-03-23info:eu-repo/semantics/openAccess