The synthesis of 1,2,3,6,6a,7-hexahydro-7-methyl-5-imino-1H-pyrrolo[1,2-c]imidazolo[5,4-b]indole

Pla Queral, DanielMills, KeithJoule, John A.Albericio Palomera, FernandoÁlvarez Domingo, Mercedes2015-02-042015-02-042009-05-011551-7012https://hdl.handle.net/2445/62365N-3-(1-Methylindol-3-yl)propan-N-(2,2,2-trichloroethoxysulfonyl)guanidine was synthesized from 3-formyl-1-methylindole in six steps and subjected to conditions intended to convert the side-chain into a 2-iminotetrahydropyrimidine- containing product, of relevance to a possible synthesis of the aplicyanins. An alternative reaction course was observed, resulting in the formation of a new tetracyclic system.10 p.application/pdfengcc-by-nc (c) Pla Queral, Daniel et al., 2009http://creativecommons.org/licenses/by-nc/3.0/esSíntesi orgànicaMedicaments antineoplàsticsCompostos de nitrogenAziridinesÀcids nucleicsOrganic synthesisAntineoplastic agentsNitrogen compoundsAziridinesNucleic acidsThe synthesis of 1,2,3,6,6a,7-hexahydro-7-methyl-5-imino-1H-pyrrolo[1,2-c]imidazolo[5,4-b]indoleinfo:eu-repo/semantics/article5722862015-02-04info:eu-repo/semantics/openAccess