Stereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosine

Fernandez-Valparis, JavierRomea, PedroUrpí Tubella, Fèlix2019-05-032020-03-192019-03-191434-193Xhttps://hdl.handle.net/2445/132634Protected peptides containing an anti b-hydroxy tyrosine are synthesized in a straightforward and highly efficient manner through the direct and stereoselective addition of N-azidoacetyl-4-isopropyl-1,3-thiazolidine-2-thione to dialkyl acetals catalyzed by a nickel(II) complex, the forging of an amide bond by removal of the chiral auxiliary with an amino ester, and final coupling with a third amino acid.8 p.application/pdfeng(c) Wiley-VCH, 2019PèptidsEstereoquímicaQuiralitatPeptidesStereochemistryChiralityStereoselective synthesis of protected peptides containing an anti β‐Hydroxy tyrosineinfo:eu-repo/semantics/article6899242019-05-03info:eu-repo/semantics/openAccess