Martín-Gago, PabloGomez-Caminals, MarcRamón, RosarioVerdaguer i Espaulella, XavierMartin-Malpartida, PauAragón Altarriba, EricFernández-Carneado, JimenaPonsati, BertaLópez-Ruiz, PilarCortes, María AliciaColás, BegoñaMacías Hernández, María J.Riera i Escalé, Antoni2021-05-072021-05-072012-021433-7851https://hdl.handle.net/2445/177099Going through the motions: Somatostatin analogues having greater conformational rigidity than somatostatin have been prepared by substituting Phe residues in the native sequence with mesityl alanine (Msa; see structure). The analogues show high affinity for SSTR receptors, thus showing that fine‐tuning of noncovalent interactions between amino acid side chains can modulate peptide affinity and selectivity.6 p.application/pdfeng(c) Wiley-VCH, 2012SomatostatinaPèptidsSomatostatinPeptidesinfo:eu-repo/semantics/article6062582021-05-07info:eu-repo/semantics/openAccess