Pruna Morales, RaquelPalacio Bonet, FranciscoBaraket, AbdoullatifBausells, JoanErrachid, AbdelhamidLópez de Miguel, Manuel2020-03-132020-03-132017-08-282504-3900https://hdl.handle.net/2445/152689The development of miniaturized potentiostats capable of measuring in a wide range of conditions and with full characteristics (e.g., wide bandwidth and capacitive/inductive contribution to sensor's impedance) is still an unresolved challenge in bioelectronics. We present a simple analogue design coupled to a digital filter based on a lock-in amplifier as an alternative to complex architectures reported hitherto. A low-cost, miniaturized and fully integrated acquisition electronic system was developed, tested for a fully integrated three-lead electrochemical biosensor and benchmarked against a commercial potentiostat. The portable potentiostat was coupled to an array of miniaturized gold working electrodes to perform complex impedance analyses for tumor necrosis factor α (TNF-α) cytokine detection. This wearable potentiostat is very promising for the development of low-cost point-of-care (POC) with low power consumption.4 p.application/pdfengcc-by (c) Pruna Morales, Raquel et al., 2017http://creativecommons.org/licenses/by/3.0/esEspectroscòpia d'impedànciaInsuficiència cardíacaBioelectrònicaAmplificadors (Electrònica)Impedance spectroscopyHeart failureBioelectronicsAmplifiers (Electronics)info:eu-repo/semantics/article6782082020-03-13info:eu-repo/semantics/openAccess