Pérez Sisqués, LeticiaSancho Balsells, AnnaSolana Balaguer, JúliaCampoy Campos, GenísVives Isern, MarcelSoler Palazón, FerranAnglada Huguet, MartaLópez Toledano, Miguel ÁngelMandelkow, Eva MariaAlberch i Vié, Jordi, 1959-Giralt Torroella, AlbertMalagelada Grau, Cristina2024-02-162024-02-162021-06-152041-4889https://hdl.handle.net/2445/207668We found an unanticipated recovery of several gliosis hallmarks and inflammasome key proteins upon neuronal RTP801 downregulation in the 5xFAD mice. Altogether our results suggest that RTP801 could be a potential future target for theranostic studies since it could be a biomarker of neuroinflammation and neurotoxicity severity of the disease and, at the same time, a promising therapeutic target in the treatment of AD.13 p.application/pdfengcc-by (c) Pérez Sisqués, Leticia et al., 2021http://creativecommons.org/licenses/by/3.0/es/CervellMort cel·lularMalaltia d'AlzheimerMalalties cerebralsProteïnesBrainCell deathAlzheimer's diseaseBrain diseasesProteinsinfo:eu-repo/semantics/article7130342024-02-16info:eu-repo/semantics/openAccess34131105