Coussanes, GuilhemJakobi, HaraldLindell, StephenBonjoch i Sesé, Josep2019-02-132019-05-162018-05-160947-6539https://hdl.handle.net/2445/128198A cyanoborohydride-promoted radical cyclization methodology has been developed to access α-chlorolactams in a simple and efficient way, using NaBH3CN and trichloroacetamides easily available from allylic and homoallylic secondary amines. This methodology allowed the synthesis of a library of αchlorolactams (mono and bicyclic), which were tested for herbicidal activity, trans-3-chloro-4-methyl-1-(3-trifluoromethyl)phenyl-2-pyrrolidinone being the most active.6 p.application/pdfeng(c) Wiley-VCH, 2018LactamesHerbicidesRadicals (Química)Síntesi orgànicaLactamsHerbicidesRadicals (Chemistry)Organic synthesisinfo:eu-repo/semantics/article6832232019-02-13info:eu-repo/semantics/openAccess29603478