Fernández Dueñas, VíctorPérez Arévalo, AndreaAltafaj, XavierFerré, SergiCiruela Alférez, Francisco2020-01-162020-01-162017-11-221662-4548https://hdl.handle.net/2445/148041Parkinson's disease (PD) is a progressive, neurodegenerative disorder that affects ~1% of individuals over the age of 60, which turns to 5% in subjects up to 85 years (de Lau and Breteler, 2006). On the other hand, a form of PD, called early-onset PD (EOPD), arises at an earlier age (<45; Bonifati et al., 2005; Ylikotila et al., 2015). EOPD patients generally display a slower progression of the disease and present a better response to dopaminergic treatments; however, they may finally develop a full PD symptomatology (i.e., bradykinesia, resting tremor, muscular rigidity and postural instability, drug-induced dyskinesia; Olgiati et al., 2016).4 p.application/pdfengcc-by (c) Fernández Dueñas, Víctor et al., 2017http://creativecommons.org/licenses/by/3.0/esMalaltia de ParkinsonOligòmersAdenosinaParkinson's diseaseOligomersAdenosineAdenosine A1-A2A Receptor Heteromer as a Possible Target for Early-Onset Parkinson's Diseaseinfo:eu-repo/semantics/article6827092020-01-16info:eu-repo/semantics/openAccess29213228