Ocaña i Rebull, JordiSánchez Olavarría, María PilarSànchez, Àlex (Sànchez Pla)Carrasco Jordan, Josep Lluís2010-03-082010-03-082008-06-05https://hdl.handle.net/2445/11512Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carry- over problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference is highlighted. A new distance-based method to determine whether two gene lists are equivalent in terms of their annotations in the Gene Ontology illustrates these ideas. We end with a general discussion and some suggestions for future research.4 p.96403 bytesapplication/pdfengcc-by-nc-nd, (c) Ocaña et al., 2008http://creativecommons.org/licenses/by-nc-nd/2.5/es/Mètodes estadísticsEquivalència terapèutica dels medicamentsStatistical methodsTherapeutic equivalency in drugsinfo:eu-repo/semantics/workingPaperinfo:eu-repo/semantics/openAccess