Fico, GiovannaOliva, VincenzoDe Prisco, MicheleFortea, LauraFortea, AdrianaGiménez Palomo, AnnaAnmella, GerardHidalgo Mazzei, DiegoVazquez, MireiaGómez-Ramiro, MartaCarreras Marcos, BernatMurru, AndreaRadua, JoaquimMortier, PhilippeVilagut Saiz, GemmaAmigo, FrancoFerrer Vinardell, MarcGarcía Mieres, HelenaVieta i Pascual, Eduard, 1963-Alonso, Jordi2025-04-072025-04-072023-10-010165-0327https://hdl.handle.net/2445/220304Introduction: Psychological, socio-demographics, and clinical factors play an important role in patients with COVID-19, but their relationship is complex. The network approach might be used to disentangle complex interactions in different systems. Using data from a multicentre, cross-sectional, survey among patients with COVID-19 in Spain (July-November 2020), we investigated the network structure of mental disorders symptoms, social support, and psychological resilience, and changes in network structures according to the presence of a pre-existing mental disorder or hospitalization for COVID-19. Methods: Subjects completed a survey to evaluate sociodemographic characteristics, COVID-19 infection status, resilience, social support, and symptoms of depression, anxiety disorders, post traumatic stress disorder, panic attacks, and substance use disorder. 2084 patients with COVID-19 were included in the analysis. Network analysis was conducted to evaluate network and bridge centrality, and the network properties were compared between COVID-19 patients with and without a history of lifetime mental disorder, and between hospitalized and non-hospitalized patients. Limitations: Generalization of our findings may be difficult since differences in network connectivity may exist in different populations or samples. Results: Anxiety and depression showed high centrality in patients with COVID-19 and anxiety showed the highest bridge influence in the network. Resilience and social support showed a low influence on mental disorder symptoms. Global network estimations show no statistically significant changes between patients with and without pre-existing mental disorders or between hospitalized and non-hospitalized patients. Conclusions: Anxiety might be a key treatment target in patients with COVID-19 since its treatment might prevent other mental health adverse outcomes.60 p.application/pdfengcc-by-nc-nd (c) Elsevier B.V., 2023http://creativecommons.org/licenses/by-nc-nd/4.0/Resiliència (Tret de la personalitat)AnsietatCOVID-19Salut mentalDepressió psíquicaResilience (Personality trait)AnxietyCOVID-19Mental healthMental depressioninfo:eu-repo/semantics/article7382432025-04-07info:eu-repo/semantics/openAccess