Romaguera, RafaelGómez Hospital, Joan AntoniSánchez Elvira, GuillermoGómez Lara, JosepFerreiro, José LuisRoura i Ferrer, GerardGracida Blancas, MontserratHoms, SilviaTeruel, Luís M.Cequier Fillat, Àngel R.2020-02-252020-02-252013-02-180896-4327https://hdl.handle.net/2445/151121Objectives: To assess the usefulness of the MGuard stent in patients with ST‐segment elevation myocardial infarction (STEMI) in whom a high thrombus burden persists after manual aspiration. Background: In some patients with STEMI, a high thrombus burden may persist after manual aspiration. These patients may be at high risk of distal embolization and therefore impaired myocardial reperfusion. The MGuard is a novel mesh‐covered stent designed to minimize thrombus embolization. Methods: Single‐arm, prospective registry of patients with STEMI and high thrombus burden after aggressive thrombus aspiration treated with the MGuard stent. High thrombus burden was defined as thrombus burden grade 4 or 5 according to the TIMI score. Lesions with a side branch ≥2 mm and patients with cardiogenic shock were not included. The study end‐points were proportion of final TIMI 3 flow, normal myocardial blush, and complete ST‐segment resolution. Results: Fifty‐six patients were included. After MGuard stent implantation >85% of cases had thrombus score = 0. Final TIMI 3 flow was achieved in 82% of cases, normal myocardial blush in 55%, and complete ST‐segment resolution in 59%. Occlusion of a side branch (<2 mm) occurred in 2 cases (3.5%), embolization to a distal branch in 5 cases (8.9%), and transient no‐reflow in 4 cases (7.1%). Major adverse cardiac events rate at 9 months was 3.6%, including 1 definite acute stent thrombosis and 1 target‐vessel revascularization. Conclusions: The MGuard stent may be useful to prevent distal embolization in patients with STEMI and high thrombus burden despite mechanical aspiration.7 p.application/pdfengcc-by (c) Romaguera, Rafael et al., 2013http://creativecommons.org/licenses/by/3.0/esInfart de miocardiPròtesis de StentMyocardial infarctionStents (Surgery)info:eu-repo/semantics/article6330612020-02-25info:eu-repo/semantics/openAccess