Vinardell Martínez-Hidalgo, Ma. PilarMaddaleno Jiménez, Adriana SolangeMitjans Arnal, Montserrat2024-04-052024-04-052024-03-252079-9284https://hdl.handle.net/2445/209387<p>Photoallergy, a unique form of skin sensitization induced by specific compounds under</p><p>ultraviolet irradiation, has traditionally been investigated using animals. However, the prohibition of</p><p>animal testing for the assessment of cosmetic ingredients in Europe and other countries underscores</p><p>the necessity for in vitro or in silico alternative methods. Currently, there are no validated methods for</p><p>assessing photoallergy or photosensitization, presenting a significant challenge in the development of</p><p>new cosmetic ingredients. This review examines the landscape of alternative methods for detecting</p><p>photosensitization, emphasizing recent publications, and considering the underlying principles of</p><p>the different proposed assays.</p>1 p.application/pdfengcc-by (c) Maddaleno, A.S. et al., 2024http://creativecommons.org/licenses/by/4.0/Al·lèrgiaPellCosmèticsExperimentació animalAllergySkinCosmeticsAnimal experimentationinfo:eu-repo/semantics/article7476042024-04-05info:eu-repo/semantics/openAccess