De Prisco, MicheleOliva, VincenzoFico, GiovannaFornaro, MicheleDe Bartolomeis, AndreaSerretti, AlessandroVieta i Pascual, Eduard, 1963-Murru, Andrea2023-03-232023-03-232022-11-010149-7634https://hdl.handle.net/2445/195849Emotion dysregulation (ED) is characterized by rigid and frequent use of maladaptive emotion regulation (ER) strategies. Conceptualized as a transdiagnostic feature, ED may occur in both clinical and non-clinical populations, including people diagnosed with bipolar disorder (BD) and their first-degree relatives (FDRs), though expected to manifest with differential clinical features. To this end, we conducted a systematic review and meta-analysis of the literature comparing people with BD to healthy controls (HCs) or FDRs, from inception up to November 25, 2021, across major databases. Random-effects meta-analyses considered twenty-eight studies assessing ER/ED with a validated scale. Patients with BD differed from HCs in adopting more maladaptive ER strategies, such as rumination, risk-taking behaviors, negative focus, and less adaptive ones. Unaffected FDRs differed from people with BD, yet to a lower extent, suggesting that ED may span a continuum. ED in BD should be widely explored to better understand its course and management, with specific interventions aimed at reducing its burden on both high-risk and full-threshold populations.17 p.application/pdfengcc-by-nc-nd (c) De Prisco, Michele et al., 2022https://creativecommons.org/licenses/by-nc-nd/4.0/Trastorn bipolarTrastorns afectiusEmocionsMetaanàlisiAdaptació (Psicologia)Manic-depressive illnessAffective disordersEmotionsMeta-analysisAdaptability (Psychology)info:eu-repo/semantics/article7262972023-03-23info:eu-repo/semantics/openAccess36243194