Penela, DiegoMartinez, MikelFernández Armenta, JuanAguinaga, LuisTercedor, LuisOrdóñez, AugustoAcosta, JuanMartí Almor, JulioBisbal, FelipeRossi, LucaBorràs, RogerLinhart, MarkusSoto Iglesias, DavidJáuregui Garrido, BeatrizOrtiz Pérez, José TomásPerea Palazón, Rosario JesúsBosch Genover, XavierMont Girbau, LluísBerruezo Sánchez, Antonio2026-01-092026-01-092019-031355-6037https://hdl.handle.net/2445/225205Objective This study aims to evaluate the influence of myocardial scar after premature ventricular complexes (PVC) ablation in patients with left ventricular (LV) dysfunction. Methods 70 consecutive patients (58±11 years, 58 (83%) men, 23% (18–32) mean PVC burden) with LV dysfunction and frequent PVCs submitted for ablation were included. A late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) was performed prior to the ablation and a quantitative and qualitative analysis of the scar was done. Results Left ventricular ejection fraction progressively improved from 34.3%±9% at baseline to 44.4%±12% at 12 months (p<0.01) and 48 (69%) patients were echocardiographic responders. New York Heart Association class improved from 1.96±0.9 points at baseline to 1.36±0.6 at 12 months (p<0.001). Brain natriuretic peptide decreased from 120 (60–284) to 46 (23–81) pg/mL (p=0.04). Twenty-nine (41%) patients showed scar in the preprocedural LGE-CMR with a mean scar mass of 10.4 (5–20) g. Mean scar mass was significantly smaller in responders than in non-responders (0 (0–4.7) g vs 2 (0–14) g, respectively, p=0.017). PVC burden reduction (OR 1.09 (1.01–1.16), p=0.02) and scar mass (OR 0.9 (0.81–0.99), p=0.04) were independent predictors of response, but the former showed a higher accuracy. Conclusions Presence of myocardial scar modulates, but does not preclude, the probability of response to PVC ablation in patients with LV dysfunction.19 p.application/pdfeng(c) Penela, D. et al., 2019Infart de miocardiAblació percutàniaVentricles cardíacsMyocardial infarctionCatheter ablationVentricle of heartinfo:eu-repo/semantics/article6859562026-01-09info:eu-repo/semantics/openAccess30242139