González-Vargas, CamiloSerrano i Plana, NúriaAriño Blasco, CristinaSalazar, RicardoEsteban i Cortada, MiquelDíaz Cruz, José Manuel2017-10-022017-10-022017-09-172227-9040https://hdl.handle.net/2445/116084This work deals with the development of screen-printed carbon electrodes modified with L-glutamic acid via two different approaches: electropolymerization (SPCE/PGA) and aryl diazonium electrochemical grafting (SPCE/EGA). SPCE/PGA and SPCE/EGA were analytically compared in the determination of hydrochlorothiazide (HCTZ) by differential pulse voltammetry. Both electrochemical characterization and analytical performance indicate that SPCE/EGA is a much better sensor for HCTZ. The detection and quantification limits were at the level of micromol L-1 with a very good linearity in the studied concentration range. In addition, the proposed SPCE/EGA was successfully applied for the determination of HCTZ in an anti-hypertensive drug with high reproducibility and good trueness.12 p.application/pdfengcc-by (c) González-Vargas, Camilo et al., 2017http://creativecommons.org/licenses/by/3.0/esAnàlisi electroquímicaVoltametriaElectrochemical analysisVoltammetryinfo:eu-repo/semantics/article6733722017-10-02info:eu-repo/semantics/openAccess