Camps García, PelayoGómez Nadal, TàniaOtermin Esteras, AneFont Bardia, Ma. Mercedes2017-12-042017-12-042017-05-311420-3049https://hdl.handle.net/2445/1184657a-(Methoxycarbonyl)-N-methyl-1,3a,5,6,7,7a-hexahydro-4H-1,4,6-(epiethane[1,1,2]triyl) indene-4,9-dicarboximide has been prepared through a modification of a previous synthetic sequence, in which the benzyloxymethyl hydroxyl protecting group has been replaced by methoxymethyl, to avoid the apparent formation of a benzyl ester derivative as a side product. The overall yield of the new synthetic sequence is comparable to the previous one. Two advantages of the new procedure are: (a) no benzyl ester was formed and (b) a stereoisomeric mixture of syn- and anti-alcohols at the beginning of the synthetic sequence could be separated and the rest of the synthesis could be carried out with the main syn-stereoisomer instead of the corresponding stereoisomeric mixture as it was the case in the previous process.15 p.application/pdfengcc-by (c) Camps García, Pelayo et al., 2017http://creativecommons.org/licenses/by/3.0/esSíntesi orgànicaCompostos policíclicsDifracció de raigs XOrganic synthesisPolycyclic compoundsX-rays diffractioninfo:eu-repo/semantics/article6718252017-12-04info:eu-repo/semantics/openAccess28561800