Machine-Learning QSAR Model for Predicting Activity against Malaria Parasite's Ion Pump PfATP4 and In Silico Binding Assay Validation

Lopez Del Rio, AngelaLlorach Parés, LauraPerera Lluna, AlexandreAvila, ConxitaNonell Canals, AlfonsSánchez Martínez, Melchor2020-03-132020-03-132017-09-082504-3900https://hdl.handle.net/2445/152685Malaria is a mosquito-borne infectious disease caused by parasitic protozoans of the genus Plasmodium. Although different effective antimalarial medicines have been developed, there is serious concern that parasites are developing widespread resistance to these drugs. To avoid this, now the efforts are concentrated on treating the malaria inside the Anopheles mosquito.1 p.application/pdfengcc-by (c) Lopez Del Rio, Angela et al., 2017http://creativecommons.org/licenses/by/3.0/esMalalties infecciosesMalàriaResistència als medicamentsInsectes paràsitsAnophelesCommunicable diseasesMalariaDrug resistanceParasitic insectsAnophelesMachine-Learning QSAR Model for Predicting Activity against Malaria Parasite's Ion Pump PfATP4 and In Silico Binding Assay Validationinfo:eu-repo/semantics/article6802732020-03-13info:eu-repo/semantics/openAccess