Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/100268
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Conde Sala, Josep Lluís | - |
dc.contributor.author | Turró-Garriga, Oriol | - |
dc.contributor.author | Piñan Hernández, Sara | - |
dc.contributor.author | Portellano Ortiz, Cristina | - |
dc.contributor.author | Viñas-Diez, Vanesa | - |
dc.contributor.author | Gascón-Bayarri, Jordi | - |
dc.contributor.author | Reñé Ramírez, Ramon | - |
dc.date.accessioned | 2016-07-08T14:43:19Z | - |
dc.date.available | 2016-07-08T14:43:19Z | - |
dc.date.issued | 2015-04-15 | - |
dc.identifier.issn | 0885-6230 | - |
dc.identifier.uri | http://hdl.handle.net/2445/100268 | - |
dc.description.abstract | Objectives: Neuropsychiatric symptoms and anosognosia are known to influence the perceived quality of life of patients (QoL-p) with Alzheimer's disease (AD). This study analysed their impact on patient and caregiver ratings of QoL-p and how these ratings changed in relation to the severity of dementia. Methods: A baseline sample of 221 patients and caregivers was followed up over 24 months. Instruments: Neuropsychiatric Inventory (NPI), Anosognosia Questionnaire-Dementia (AQ-D), Quality of Life-Alzheimer's Disease (QoL-AD), and the Global Deterioration Scale (GDS). Longitudinal data were analysed using generalized linear models. Results: In the multivariate analysis, greater anosognosia was always associated with higher ratings of QoL-p among patients, especially at 24 months (p < 0.001), and with more negative ratings among caregivers, especially at baseline (p < 0.001). A higher total NPI score was associated with a more negative rating of QoL-p among caregivers (p < 0.001), and it also had a smaller negative effect on patients' self-ratings (p = 0.001). The neuropsychiatric symptoms (NPI) associated with a more negative view of QoL-p were depression, for patients' self-ratings, and apathy and agitation for caregiver ratings. The discrepancy between patient and caregiver ratings increased in line with the severity of dementia. Conclusion: Neuropsychiatric symptoms and anosognosia have differential effects on patient and caregiver ratings of the quality of life of patients with Alzheimer's disease. Key words: Alzheimer's disease, quality of life, anosognosia, neuropsychiatric symptoms, caregivers, patients. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | John Wiley & Sons | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1002/gps.4298/abstract | - |
dc.relation.ispartof | International Journal of Geriatric Psychiatry, 2015 | - |
dc.relation.uri | http://dx.doi.org/10.1002/gps.4298/abstract | - |
dc.rights | (c) John Wiley & Sons, 2015 | - |
dc.source | Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) | - |
dc.subject.classification | Malaltia d'Alzheimer | - |
dc.subject.classification | Qualitat de vida | - |
dc.subject.classification | Neuropsiquiatria | - |
dc.subject.other | Alzheimer's disease | - |
dc.subject.other | Quality of life | - |
dc.subject.other | Neuropsychiatry | - |
dc.title | Effects of anosognosia and neuropsychiatric symptoms on the quality of life of patients with alzheimer's disease: a 24-month follow-up study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 651788 | - |
dc.date.updated | 2016-07-08T14:43:24Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Effects of anosognosia. IJGP.pdf | 249.97 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.