Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/100753
Title: Alcohol intake, wine consumption and the development of depression: the PREDIMED study
Author: Gea, Alfredo
Beunza, J. J.
Estruch Riba, Ramon
Sánchez-Villegas, A.
Salas-Salvadó, J.
Buil-Cosiales, P.
Gómez-Gracia, E.
Covas Planells, María Isabel
Corella Piquer, Dolores
Fiol, Montserrat
Arós, Fernando
Lapetra, José
Lamuela Raventós, Rosa Ma.
Wärnberg, J.
Pintó Sala, Xavier
Serra Majem, Lluís
Martínez-González, Miguel Ángel, 1957-
Keywords: Consum d'alcohol
Vi
Depressió psíquica
Drinking of alcoholic beverages
Wine
Mental depression
Issue Date: 30-Aug-2013
Publisher: BioMed Central
Abstract: Background: Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake. Methods: We followed-up 5,505 high-risk men and women (55 to 80 y) of the PREDIMED Trial for up to seven years. Participants were initially free of depression or a history of depression, and did not have any history of alcohol-related problems. A 137-item validated food frequency questionnaire administered by a dietician was repeated annually to assess alcohol intake. Participants were classified as incident cases of depression when they reported a new clinical diagnosis of depression, and/or initiated the use of antidepressant drugs. Cox regression analyses were fitted over 23,655 person-years. Results: Moderate alcohol intake within the range of 5 to 15 g/day was significantly associated with lower risk of incident depression (hazard ratio (HR) and 95% confidence interval (95% CI) = 0.72 (0.53 to 0.98) versus abstainers). Specifically, wine consumption in the range of two to seven drinks/week was significantly associated with lower rates of depression (HR (95% CI) = 0.68 (0.47 to 0.98)). Conclusions: Moderate consumption of wine may reduce the incidence of depression, while heavy drinkers seem to be at higher risk.
Note: Reproducció del document publicat a: http://dx.doi.org/10.1186/1741-7015-11-192
It is part of: BMC Medicine, 2013, vol. 11, num. 192
Related resource: http://dx.doi.org/10.1186/1741-7015-11-192
URI: http://hdl.handle.net/2445/100753
ISSN: 1741-7015
Appears in Collections:Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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