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Title: Life at the mesoscale: the self-organised cytoplasm and nucleoplasm
Author: Sear, Richard P.
Pagonabarraga Mora, Ignacio
Flaus, Andrew
Keywords: Citosquelet
Issue Date: 2015
Publisher: BioMed Central
Abstract: Abstract The cell contains highly dynamic structures exploiting physical principles of self-organisation at the mesoscale (100 nm to 10 μ m). Examples include non-membrane bound cytoplasmic bodies, cytoskeleton-based motor networks and multi-scale chromatin organisation. The challenges of mesoscale self-organisation were discussed at a CECAM workshop in July 2014. Biologists need approaches to observe highly dynamic, low affinity, low specificity associations and to perturb single structures, while biological physicists and biomathematicians need to work closely with biologists to build and validate quantitative models. A table of terminology is included to facilitate multidisciplinary efforts to reveal the richness and diversity of mesoscale cell biology. Keywords: Workshop report, Self-organisation, Mesoscale, Cell biology, Cytoskeleton, Cytoplasmic bodies, Chromatin
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It is part of: BMC Biophysics, 2015, vol. 8, p. 4
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ISSN: 2046-1682
Appears in Collections:Articles publicats en revistes (Física de la Matèria Condensada)

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