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Title: Antituberculosis drug isoniazid degraded by electro-Fenton and photoelectro-Fenton processes using a boron-doped diamond anode and a carbon-PTFE air-diffusion cathode
Author: Guelfi, Diego R.V.
Gozzi, Fábio
Sirés Sadornil, Ignacio
Brillas, Enric
Machulek Jr., Amílcar
De Oliveira, Silvio C.
Keywords: Depuració d'aigües residuals
Purification of sewage
Issue Date: 27-Apr-2018
Publisher: Springer Verlag
Abstract: Solutions with 0.65 mM of the antituberculosis drug isoniazid (INH) in 0.050 M Na2SO4 at pH 3.0 were treated by electro-Fenton (EF) and UVA photoelectro-Fenton (PEF) processes using a cell with a BDD anode and a carbon-PTFE air-diffusion cathode. The influence of current density on degradation, mineralization rate, and current efficiency has been thoroughly evaluated in EF. The effect of the metallic catalyst (Fe2+ or Fe3+) and the formation of products like short-chain linear aliphatic carboxylic acids were assessed in PEF. Two consecutive pseudo-first-order kinetic regions were found using Fe2+ as catalyst. In the first region, at short time, the drug was rapidly oxidized by ●OH, whereas in the second region, at longer time, a resulting Fe(III)-INH complex was much more slowly removed by oxidants. INH disappeared completely at 300 min by EF, attaining 88 and 94% mineralization at 66.6 and 100 mA cm-2, respectively. Isonicotinamide and its hydroxylated derivative were identified as aromatic products of INH by GC-MS and oxalic, oxamic, and formic acids were quantified by ion-exclusion HPLC. The PEF treatment of a real wastewater polluted with the drug led to slower INH and TOC abatements because of the parallel destruction of its natural organic matter content.
Note: Versió postprint del document publicat a:
It is part of: Environmental Science and Pollution Research, 2018, vol. 26, num. 5, p. 4415-4425
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ISSN: 0944-1344
Appears in Collections:Articles publicats en revistes (Ciència dels Materials i Química Física)

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