Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/149376
Title: | Stereoselective decarboxylative alkylation of titanium(IV) enolates with diacyl peroxides |
Author: | Gómez Palomino, Alejandro Pérez-Palau, Marina Romea, Pedro Urpí Tubella, Fèlix Del Olmo, Marc Hesse, Timo Fleckenstein, Sonja Gómez-Bengoa, Enrique Sotorríos, Lía Font Bardia, Ma. Mercedes |
Keywords: | Estereoquímica Titani Stereochemistry Titanium |
Issue Date: | 3-Jan-2020 |
Publisher: | American Chemical Society |
Abstract: | Simple treatment of chiral titanium(IV) enolates with diacyl peroxides produces highly diastereoselective decarboxylative alkylations to efficiently deliver the corresponding adducts, most of which are not accessible through any of the current alkylating procedures. Such an unprecedented alkylation proceeds through an SET process that triggers the decomposition of the peroxide into a carbon-centered radical that finally combines with the resulting Cα radical. The procedure has been applied to the enantioselective synthesis of arundic acid. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.9b04148 |
It is part of: | Organic Letters, 2020, vol. 22, num. 1, p. 199-203 |
URI: | http://hdl.handle.net/2445/149376 |
Related resource: | https://doi.org/10.1021/acs.orglett.9b04148 |
ISSN: | 1523-7060 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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